Quantitative Imaging Methods Lab
Departments of Radiology and Medical Physics

Publications

    2021

  1. Navaratna R, Zhao R, Colgan TJ, Hu HH, Bydder M, Yokoo T, Bashir MR, Middleton MS, Serai SD, Malyarenko D, Chenevert T, Smith M, Henderson W, Hamilton G, Shu Y, Sirlin CB, Tkach JA, Trout AT, Brittain JH, Hernando D, Reeder SB and Committee RQIBAPDFFB. Temperature-corrected proton density fat fraction estimation using chemical shift-encoded MRI in phantoms. Magnetic resonance in medicine. 2021 July;86:69-81. DOI PMID
  2. Muehler MR, Vigen K, Hernando D, Zhu A, Colgan TJ and Reeder SB. Reproducibility of liver R2* quantification for liver iron quantification from cardiac R2* acquisitions. Abdominal radiology (New York). 2021 May DOI PMID
  3. Kasza I, Kühn J-P, Völzke H, Hernando D, Xu YG, Siebert JW, Gibson AL, Yen C-LE, Nelson DW, MacDougald OA, Richardson NE, Lamming DW, Kern PA and Alexander CM. Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human. The Journal of physiology. 2021 March DOI PMID
  4. Hu HH, Yokoo T, Bashir MR, Sirlin CB, Hernando D, Malyarenko D, Chenevert TL, Smith MA, Serai SD, Middleton MS, Henderson WC, Hamilton G, Shaffer J, Shu Y, Tkach JA, Trout AT, Obuchowski N, Brittain JH, Jackson EF, Reeder SB and Committee RQIBAPB. Linearity and Bias of Proton Density Fat Fraction as a Quantitative Imaging Biomarker: A Multicenter, Multiplatform, Multivendor Phantom Study. Radiology. 2021 March;298:640-651. DOI PMID
  5. Colgan TJ, Zhao R, Roberts NT, Hernando D and Reeder SB. Limits of Fat Quantification in the Presence of Iron Overload. Journal of magnetic resonance imaging : JMRI. 2021 March DOI PMID
  6. Rajlawot K, Jiang T, Zhou J, Lin C, Kuang S, Chen J, Zhang Y, Yang H, Deng Y, He B, Hernando D, Reeder SB and Wang J. Accuracies of Chemical Shift In/Opposed Phase and Chemical Shift Encoded Magnetic Resonance Imaging to Detect Intratumoral Fat in Hepatocellular Carcinoma. Journal of magnetic resonance imaging : JMRI. 2021 February DOI PMID
  7. Kee Y, Sandino CM, Syed AB, Cheng JY, Shimakawa A, Colgan TJ, Hernando D and Vasanawala SS. Free-breathing , mapping of hepatic iron overload in children using 3D multi-echo UTE cones MRI. Magnetic resonance in medicine. 2021 January DOI PMID

    8. 2020

  8. Pewowaruk R, Rutkowski D, Hernando D, Kumapayi BB, Bushman W and Roldán-Alzate A. A pilot study of bladder voiding with real-time MRI and computational fluid dynamics. PloS one. 2020;15:e0238404. DOI PMID
  9. Roberts NT, Hinshaw LA, Colgan TJ, Ii T, Hernando D and Reeder SB. B0 and B 1 inhomogeneities in the liver at 1.5 T and 3.0 T. Magnetic resonance in medicine. 2020 October DOI PMID
  10. Lawrence EM, Roberts NT, Hernando D, Mao L and Reeder SB. Effect of noise and estimator type on bias for analysis of liver proton density fat fraction. Magnetic resonance imaging. 2020 October;74:244-249. DOI PMID
  11. Zhao R, Hamilton G, Brittain JH, Reeder SB and Hernando D. Design and evaluation of quantitative MRI phantoms to mimic the simultaneous presence of fat, iron, and fibrosis in the liver. Magnetic resonance in medicine. 2020 August DOI PMID
  12. Luo H, Zhu A, Wiens CN, Starekova J, Shimakawa A, Reeder SB, Johnson KM and Hernando D. Free-breathing liver fat and , quantification using motion-corrected averaging based on a nonlocal means algorithm. Magnetic resonance in medicine. 2020 August DOI PMID
  13. Hernando D, Cook RJ, Qazi N, Longhurst CA, Diamond CA and Reeder SB. Complex confounder-corrected R2* mapping for liver iron quantification with MRI. European radiology. 2020 August DOI PMID
  14. Zhao R, Zhang Y, Wang X, Colgan TJ, Rehm JL, Reeder SB, Johnson KM and Hernando D. Motion-robust, high-SNR liver fat quantification using a 2D sequential acquisition with a variable flip angle approach. Magnetic resonance in medicine. 2020 April DOI PMID
  15. Zhang Y, Wells SA, Triche BL, Kelcz F and Hernando D. Stimulated-echo diffusion-weighted imaging with moderate b values for the detection of prostate cancer. European radiology. 2020 February DOI PMID
  16. Wells SA, Schubert T, Motosugi U, Sharma SD, Campo CA, Kinner S, Woo KM, Hernando D and Reeder SB. Pharmacokinetics of Ferumoxytol in the Abdomen and Pelvis: A Dosing Study with 1.5- and 3.0-T MRI Relaxometry. Radiology. 2020 January;294:108-116. DOI PMID

    17. 2019

  17. Yi SY, Barnett BR, Torres-Velázquez M, Zhang Y, Hurley SA, Rowley PA, Hernando D and Yu J-PJ. Detecting Microglial Density With Quantitative Multi-Compartment Diffusion MRI. Frontiers in neuroscience. 2019;13:81. DOI PMID
  18. Wang X, Hernando D and Reeder SB. Phase-based T2 mapping with gradient echo imaging. Magnetic resonance in medicine. 2019 December DOI PMID
  19. Wang X, Colgan TJ, Hinshaw LA, Roberts NT, Bancroft LCH, Hamilton G, Hernando D and Reeder SB. T1-corrected quantitative chemical shift-encoded MRI. Magnetic resonance in medicine. 2019 November DOI PMID
  20. Hu HH, Branca RT, Hernando D, Karampinos DC, Machann J, McKenzie CA, Wu HH, Yokoo T and Velan SS. Magnetic resonance imaging of obesity and metabolic disorders: Summary from the 2019 ISMRM Workshop. Magnetic resonance in medicine. 2019 November DOI PMID
  21. Zhu A, Reeder SB, Johnson KM, Nguyen SM, Fain SB, Bird IM, Golos TG, Wieben O, Shah DM and Hernando D. Quantitative ferumoxytol-enhanced MRI in pregnancy: A feasibility study in the nonhuman primate. Magnetic resonance imaging. 2019 October;65:100-108. DOI PMID
  22. Peña-Nogales Ó, Hernando D, Aja-Fernández S and de Luis-Garcia R. Determination of optimized set of b-values for Apparent Diffusion Coefficient mapping in liver Diffusion-Weighted MRI. Journal of magnetic resonance. 2019 October;310:106634. DOI PMID
  23. Colgan TJ, Knobloch G, Reeder SB and Hernando D. Sensitivity of quantitative relaxometry and susceptibility mapping to microscopic iron distribution. Magnetic resonance in medicine. 2019 August DOI PMID
  24. Zhu A, Reeder SB, Johnson KM, Nguyen SM, Golos TG, Shimakawa A, Muehler MR, Francois CJ, Bird IM, Fain SB, Shah DM, Wieben O and Hernando D. Evaluation of a motion-robust 2D chemical shift-encoded technique for R2* and field map quantification in ferumoxytol-enhanced MRI of the placenta in pregnant rhesus macaques. Journal of magnetic resonance imaging : JMRI. 2019 July DOI PMID
  25. Zhu A, Hernando D, Johnson KM and Reeder SB. Characterizing a short T2* signal component in the liver using ultrashort TE chemical shift-encoded MRI at 1.5T and 3.0T. Magnetic resonance in medicine. 2019 July DOI PMID
  26. Kasza I, Adler D, Nelson DW, Eric Yen C-L, Dumas S, Ntambi JM, MacDougald OA, Hernando D, Porter WP, Best FA and Alexander CM. Evaporative cooling provides a major metabolic energy sink. Molecular metabolism. 2019 July DOI PMID
  27. Liu TT, Thomas S, Mclean DT, Roldan-Alzate A, Hernando D, Ricke EA and Ricke WA. Prostate enlargement and altered urinary function are part of the aging process. Aging. 2019 May;11:2653-2669. DOI PMID
  28. Zhang Y, Peña-Nogales Ó, Holmes JH and Hernando D. Motion-robust and blood-suppressed M1-optimized diffusion MR imaging of the liver. Magnetic resonance in medicine. 2019 March DOI PMID
  29. Pooler BD, Hernando D and Reeder SB. Clinical Implementation of a Focused MRI Protocol for Hepatic Fat and Iron Quantification. AJR. American journal of roentgenology. 2019 March:1-6. DOI PMID
  30. Rabanillo-Viloria I, Zhu A, Aja-Fernández S, Alberola-López C and Hernando D. Computation of exact g-factor maps in 3D GRAPPA reconstructions. Magnetic resonance in medicine. 2019 February;81:1353-1367. DOI PMID
  31. Zhang Y, Wells SA and Hernando D. Stimulated echo based mapping (STEM) of T1, T2, and apparent diffusion coefficient: Validation and protocol optimization. Magnetic Resonance in Medicine. 2019 January;81(1):167-181. DOI PMID
  32. Park CC, Hooker C, Hooker JC, Bass E, Haufe W, Schlein A, Covarrubias Y, Heba E, Bydder M, Wolfson T, Gamst A, Loomba R, Schwimmer J, Hernando D, Reeder SB, Middleton M, Sirlin CB and Hamilton G. Assessment of a high-SNR chemical-shift-encoded MRI with complex reconstruction for proton density fat fraction (PDFF) estimation overall and in the low-fat range. Journal of magnetic resonance imaging : JMRI. 2019 January;49:229-238. DOI PMID

    33. 2018

  33. Pooler BD, Hernando D, Ruby JA, Ishii H, Shimakawa A and Reeder SB. Validation of a motion-robust 2D sequential technique for quantification of hepatic proton density fat fraction during free breathing. Journal of magnetic resonance imaging : JMRI. 2018 December;48:1578-1585. DOI PMID
  34. Peña-Nogales Ó, Zhang Y, Wang X, de Luis-Garcia R, Aja-Fernández S, Holmes JH and Hernando D. Optimized Diffusion-Weighting Gradient Waveform Design (ODGD) formulation for motion compensation and concomitant gradient nulling. Magnetic Resonance in Medicine. 2018 November;81(2):989-1003. DOI PMID
  35. Zhang Y, Holmes J, Rabanillo I, Guidon A, Wells S and Hernando D. Quantitative diffusion MRI using reduced field-of-view and multi-shot acquisition techniques: Validation in phantoms and prostate imaging. Magnetic Resonance Imaging. 2018 September;51:173-181. DOI PMID
  36. Pickhardt PJ, Graffy PM, Reeder SB, Hernando D and Li K. Quantification of liver fat content with unenhanced MDCT: Phantom and clinical correlation with MRI proton density fat fraction. American Journal of Roentgenology. 2018 September;211(3):W151-W157. DOI PMID
  37. van Heeswijk RB, Colotti R, Darçot E, Delacoste J, Pellegrin M, Piccini D and Hernando D. Chemical shift encoding (CSE) for sensitive fluorine-19 MRI of perfluorocarbons with complex spectra. Magnetic Resonance in Medicine. 2018 September;79(5):2724-2730. DOI PMID
  38. Ludwig KD, Hernando D, Roberts NT, van Heeswijk RB and Fain SB. A chemical shift encoding (CSE) approach for spectral selection in fluorine-19 MRI. Magnetic Resonance in Medicine. 2018 August;79(4):2183-2189. DOI PMID
  39. Pirasteh A, Yuan Q, Hernando D, Reeder SB, Pedrosa I and Yokoo T. Inter-method reproducibility of biexponential R2 MR relaxometry for estimation of liver iron concentration. Magnetic Resonance in Medicine. 2018 May DOI PMID
  40. Knobloch G, Colgan T, Wiens CN, Wang X, Schubert T, Hernando D, Sharma SD and Reeder SB. Relaxivity of Ferumoxytol at 1.5 T and 3.0 T. Investigative Radiology. 2018 May;53(5):257-263. DOI PMID
  41. Jeong D, Raghunand N, Hernando D, Poch M, Jeong K, Eck B and Dhillon J. Quantification of sarcomatoid differentiation in renal cell carcinoma on magnetic resonance imaging. Quantitative Imaging in Medicine and Surgery. 2018 May;8(4):373-382. DOI PMID
  42. Ichikawa S, Motosugi U, Hernando D, Morisaka H, Enomoto N, Matsuda M and Onishi H. Histological grading of hepatocellular carcinomas with intravoxel incoherent motion diffusion-weighted imaging: Inconsistent results depending on the fitting method. Magnetic Resonance in Medical Sciences. 2018 April;17(2):168-173. DOI PMID
  43. Yokoo T, Serai SD, Pirasteh A, Bashir MR, Hamilton G, Hernando D, Hu HH, Hetterich H, Kühn J-P, Kukuk GM, Loomba R, Middleton MS, Obuchowski NA, Song JS, Tang A, Wu X, Reeder SB and Sirlin CB. Linearity, bias, and precision of hepatic proton density fat fraction measurements by using MR imaging: A meta-analysis. Radiology. 2018 February;286(2):486-498. DOI PMID
  44. Rabanillo I, Aja-Fernandez S, Alberola-Lopez C and Hernando D. Exact Calculation of Noise Maps and g-Factor in GRAPPA Using a k-Space Analysis. IEEE Transactions on Medical Imaging. 2018 February;37(2):480-490. DOI PMID
  45. Roberts NT, Hernando D, Holmes JH, Wiens CN and Reeder SB. Noise properties of proton density fat fraction estimated using chemical shift–encoded MRI. Magnetic Resonance in Medicine. 2018 January;80(2):685-695. DOI PMID

    46. 2017

  46. Motosugi U, Hernando D, Wiens C, Bannas P and Reeder SB. High SNR acquisitions improve the repeatability of liver fat quantification using confounder-corrected chemical shift-encoded MR imaging. Magnetic Resonance in Medical Sciences. 2017 October;16(4):332-339. DOI PMID
  47. Kühn J-P, Meffert P, Heske C, Kromrey M-L, Schmidt CO, Mensel B, Völzke H, Lerch MM, Hernando D, Mayerle J and Reeder SB. Prevalence of fatty liver disease and hepatic iron overload in a northeastern German population by using quantitative MR imaging. Radiology. 2017 September;284(3):706-716. DOI PMID
  48. Colgan TJ, Hernando D, Sharma SD and Reeder SB. The effects of concomitant gradients on chemical shift encoded MRI. Magnetic Resonance in Medicine. 2017 September;78(2):730-738. DOI PMID
  49. Campo CA, Hernando D, Schubert T, Bookwalter CA, Van Pay AJ and Reeder SB. Standardized approach for ROI-based measurements of proton density fat fraction and r2 in the liver. American Journal of Roentgenology. 2017 September;209(3):592-603. DOI PMID
  50. Sharma SD, Fischer R, Schoennagel BP, Nielsen P, Kooijman H, Yamamura J, Adam G, Bannas P, Hernando D and Reeder SB. MRI-based quantitative susceptibility mapping (QSM) and R2* mapping of liver iron overload: Comparison with SQUID-based biomagnetic liver susceptometry. Magnetic Resonance in Medicine. 2017 August;78(1):264-270. DOI PMID
  51. Horng DE, Hernando D and Reeder SB. Quantification of liver fat in the presence of iron overload. Journal of Magnetic Resonance Imaging. 2017 July;45(2):428-439. DOI PMID
  52. Wang X, Reeder SB and Hernando D. An acetone-based phantom for quantitative diffusion MRI. Journal of Magnetic Resonance Imaging. 2017 April;46(6):1683-1692. DOI PMID
  53. Hernando D, Sharma SD, Aliyari Ghasabeh M, Alvis BD, Arora SS, Hamilton G, Pan L, Shaffer JM, Sofue K, Szeverenyi NM, Welch EB, Yuan Q, Bashir MR, Kamel IR, Rice MJ, Sirlin CB, Yokoo T and Reeder SB. Multisite, multivendor validation of the accuracy and reproducibility of proton-density fat-fraction quantification at 1.5T and 3T using a fat–water phantom. Magnetic Resonance in Medicine. 2017 April;77(4):1516-1524. DOI PMID
  54. Haufe WM, Wolfson T, Hooker CA, Hooker JC, Covarrubias Y, Schlein AN, Hamilton G, Middleton MS, Angeles JE, Hernando D, Reeder SB, Schwimmer JB and Sirlin CB. Accuracy of PDFF estimation by magnitude-based and complex-based MRI in children with MR spectroscopy as a reference. Journal of Magnetic Resonance Imaging. 2017 March;46(6):1641-1647. DOI PMID
  55. Artz NS, Wiens CN, Smith MR, Hernando D, Samsonov A and Reeder SB. Accelerating fully phase-encoded MRI near metal using multiband radiofrequency excitation. Magnetic Resonance in Medicine. 2017 March;77(3):1223-1230. DOI PMID
  56. Kramer H, Pickhardt PJ, Kliewer MA, Hernando D, Chen G-H, Zagzebski JA and Reeder SB. Accuracy of liver fat quantification with advanced CT, MRI, and ultrasound techniques: Prospective comparison with MR spectroscopy. American Journal of Roentgenology. 2017 January;208(1):92-100. DOI PMID

    57. 2016

  57. Motosugi U, Bannas P, Hernando D, Rahimi MS, Holmes JH and Reeder SB. Intraindividual crossover comparison of gadoxetic acid dose for liver MRI in normal volunteers. Magnetic Resonance in Medical Sciences. 2016;15(1):60-72. DOI PMID
  58. Bannas P, Motosugi U, Hernando D, Rahimi MS, Holmes JH and Reeder SB. Combined gadoxetic acid and gadofosveset enhanced liver MRI: A feasibility and parameter optimization study. Magnetic Resonance in Medicine. 2016;75(1):318-328. DOI PMID
  59. Reeder SB, Smith MR and Hernando D. Mathematical optimization of contrast concentration for t1-weighted spoiled gradient echo imaging. Magnetic Resonance in Medicine. 2016 May;75(4):1556-1564. DOI PMID
  60. Mahlke C, Hernando D, Jahn C, Cigliano A, Ittermann T, Mössler A, Kromrey M-L, Domaska G, Reeder SB and Kühn J-P. Quantification of liver proton-density fat fraction in 7.1T preclinical MR systems: Impact of the fitting technique. Journal of Magnetic Resonance Imaging. 2016 May;44(6):1425-1431. DOI PMID
  61. Henze Bancroft LC, Strigel RM, Hernando D, Johnson KM, Kelcz F, Kijowski R and Block WF. Utilization of a balanced steady state free precession signal model for improved fat/water decomposition. Magnetic Resonance in Medicine. 2016 May;75(3):1269-1277. DOI PMID
  62. Wang X, Hernando D and Reeder SB. Sensitivity of chemical shift-encoded fat quantification to calibration of fat MR spectrum. Magnetic Resonance in Medicine. 2016 April;75(2):845-851. DOI PMID

    63. 2015

  63. Smith MR, Artz NS, Wiens C, Hernando D and Reeder SB. Characterizing the limits of MRI near metallic prostheses. Magnetic Resonance in Medicine. 2015;74(6):1564-1573. DOI PMID
  64. Sharma SD, Hernando D, Horng DE and Reeder SB. Quantitative susceptibility mapping in the abdomen as an imaging biomarker of hepatic iron overload. Magnetic Resonance in Medicine. 2015;74(3):673-683. DOI PMID
  65. Sharma SD, Artz NS, Hernando D, Horng DE and Reeder SB. Improving chemical shift encoded water-fat separation using object-based information of the magnetic field inhomogeneity. Magnetic Resonance in Medicine. 2015;73(2):597-604. DOI PMID
  66. Rehm JL, Wolfgram PM, Hernando D, Eickhoff JC, Allen DB and Reeder SB. Proton density fat-fraction is an accurate biomarker of hepatic steatosis in adolescent girls and young women. European Radiology. 2015;25(10):2921-2930. DOI PMID
  67. Motosugi U, Hernando D, Bannas P, Holmes JH, Wang K, Shimakawa A, Iwadate Y, Taviani V, Rehm JL and Reeder SB. Quantification of liver fat with respiratory-gated quantitative chemical shift encoded MRI. Journal of Magnetic Resonance Imaging. 2015;42(5):1241-1248. DOI PMID
  68. Hu HH and Hernando D. Direct water-fat imaging methods: Chemical shift-selective and chemical shift-encoded MRI. eMagRes. 2015;4(3):673-687. DOI
  69. Hernando D, Wells SA, Vigen KK and Reeder SB. Effect of hepatocyte-specific gadolinium-based contrast agents on hepatic fat-fraction and R2. Magnetic Resonance Imaging. 2015;33(1):43-50. DOI PMID
  70. Bannas P, Kramer H, Hernando D, Agni R, Cunningham AM, Mandal R, Motosugi U, Sharma SD, Munoz del Rio A, Fernandez L and Reeder SB. Quantitative magnetic resonance imaging of hepatic steatosis: Validation in ex vivo human livers. Hepatology. 2015;62(5):1444-1455. DOI PMID
  71. Baiu DC, Artz NS, McElreath MR, Menapace BD, Hernando D, Reeder SB, Grüttner C and Otto M. High specificity targeting and detection of human neuroblastoma using multifunctional anti-GD2 iron-oxide nanoparticles. Nanomedicine. 2015;10(19):2973-2988. DOI PMID
  72. Attenberger UI, Morelli J, Budjan J, Henzler T, Sourbron S, Bock M, Riffel P, Hernando D, Ong MM and Schoenberg SO. Fifty years of technological innovation: Potential and limitations of current technologies in abdominal magnetic resonance imaging and computed tomography. Investigative Radiology. 2015;50(9):584-593. DOI PMID
  73. Alexander CM, Kasza I, Yen C-LE, Reeder SB, Hernando D, Gallo RL, Jahoda CAB, Horsley V and MacDougald OA. Dermal white adipose tissue: A new component of the thermogenic response. Journal of Lipid Research. 2015;56(11):2061-2069. DOI PMID

    74. 2014

  74. Taviani V, Hernando D, Francois CJ, Shimakawa A, Vigen KK, Nagle SK, Schiebler ML, Grist TM and Reeder SB. Whole-heart chemical shift encoded water-fat MRI. Magnetic resonance in medicine. 2014;72(3):718-725. DOI PMID
  75. Kühn J-P, Jahn C, Hernando D, Siegmund W, Hadlich S, Mayerle J, Pfannmöller J, Langner S and Reeder S. T1 bias in chemical shift-encoded liver fat-fraction: Role of the flip angle. Journal of Magnetic Resonance Imaging. 2014;40(4):875-883. DOI PMID
  76. Kühn J-P, Holmes JH, Brau ACS, Iwadate Y, Hernando D and Reeder SB. Navigator flip angle optimization for free-breathing T1-weighted hepatobiliary phase imaging with gadoxetic acid. Journal of Magnetic Resonance Imaging. 2014;40(5):1129-1136. DOI PMID
  77. Kühn J-P, Hernando D, Mensel B, Krüger PC, Ittermann T, Mayerle J, Hosten N and Reeder SB. Quantitative chemical shift-encoded MRI is an accurate method to quantify hepatic steatosis. Journal of Magnetic Resonance Imaging. 2014;39(6):1494-1501. DOI PMID
  78. Hernando D, Sharma SD, Kramer H and Reeder SB. On the confounding effect of temperature on chemical shift-encoded fat quantification. Magnetic Resonance in Medicine. 2014;72(2):464-470. DOI PMID
  79. Hernando D, Levin YS, Sirlin CB and Reeder SB. Quantification of liver iron with MRI: State of the art and remaining challenges. Journal of Magnetic Resonance Imaging. 2014;40(5):1003-1021. DOI PMID
  80. Artz NS, Hernando D, Taviani V, Samsonov A, Brittain JH and Reeder SB. Spectrally resolved fully phase-encoded three-dimensional fast spin-echo imaging. Magnetic Resonance in Medicine. 2014;71(2):681-690. DOI PMID
  81. Bannas P, Hernando D, Motosugi U, Roldan A and Reeder SB. Emerging quantitative MRI biomarkers of diffuse liver disease. Clinical Liver Disease. 2014 December;4(6):129-132. DOI
  82. Bannas P, Motosugi U, Ichikawa S, Hernando D and Reeder SB. Primer on magnetic resonance imaging of the liver. Clinical Liver Disease. 2014 November;4(5):120-123. DOI

    83. 2013

  83. Poonawalla AH, Sjoberg BP, Rehm JL, Hernando D, Hines CD, Irarrazaval P and Reeder SB. Adipose tissue MRI for quantitative measurement of central obesity. Journal of Magnetic Resonance Imaging. 2013;37(3):707-716. DOI PMID
  84. Kühn J-P, Hernando D, Meffert PJ, Reeder S, Hosten N, Laqua R, Steveling A, Ender S, Schröder H and Pillich D-T. Proton-density fat fraction and simultaneous R2*estimation as an MRI tool for assessment of osteoporosis. European Radiology. 2013;23(12):3432-3439. DOI PMID
  85. Horng DE, Hernando D, Hines CDG and Reeder SB. Comparison of R2* correction methods for accurate fat quantification in fatty liver. Journal of Magnetic Resonance Imaging. 2013;37(2):414-422. DOI PMID
  86. Hernando D, Kühn J-P, Mensel B, Völzke H, Puls R, Hosten N and Reeder SB. R2* estimation using “in-phase” echoes in the presence of fat: The effects of complex spectrum of fat. Journal of Magnetic Resonance Imaging. 2013;37(3):717-726. DOI PMID
  87. Hernando D, Kramer JH and Reeder SB. Multipeak fat-corrected complex R2* relaxometry: Theory, optimization, and clinical validation. Magnetic Resonance in Medicine. 2013;70(5):1319-1331. DOI PMID
  88. Hernando D, Cook RJ, Diamond C and Reeder SB. Magnetic susceptibility as a B0 field strength independent MRI biomarker of liver iron overload. Magnetic Resonance in Medicine. 2013;70(3):648-656. DOI PMID
  89. Hansmann J, Hernando D and Reeder SB. Fat confounds the observed apparent diffusion coefficient in patients with hepatic steatosis. Magnetic Resonance in Medicine. 2013;69(2):545-552. DOI PMID
  90. Haldar JP, Hernando D and Liang Z-P. Erratum: Compressed-sensing MRI with random encoding (IEEE Transactions on Medical Imaging). IEEE Transactions on Medical Imaging. 2013;32(7):1362. DOI
  91. Bülow R, Mensel B, Meffert P, Hernando D, Evert M and Kühn J-P. Diffusion-weighted magnetic resonance imaging for staging liver fibrosis is less reliable in the presence of fat and iron. European Radiology. 2013;23(5):1281-1287. DOI PMID
  92. Aja-Ferńandez S, Luis-Garćía RD, Alberola-Ĺopez C and Hernando D. Quantitative diffusion MRI in the presence of noise: Effects of filtering and fitting technique. Optics InfoBase Conference Papers. 2013

    93. 2012

  93. Yin X, Guo Y, Li W, Huo E, Zhang Z, Nicolai J, Kleps RA, Hernando D, Katsaggelos AK, Omary RA and Larson AC. Chemical shift MR imaging methods for the quantification of transcatheter lipiodol delivery to the liver: Preclinical feasibility studies in a rodent model. Radiology. 2012;263(3):714-722. DOI PMID
  94. Reeder SB, Bice EK, Yu H, Hernando D and Pineda AR. On the performance of T 2* correction methods for quantification of hepatic fat content. Magnetic Resonance in Medicine. 2012;67(2):389-404. DOI PMID
  95. Kühn J-P, Hernando D, Muñoz Del Rio A, Evert M, Kannengiesser S, Völzke H, Mensel B, Puls R, Hosten N and Reeder SB. Effect of multipeak spectral modeling of fat for liver iron and fat quantification: Correlation of biopsy with MR imaging results. Radiology. 2012;265(1):133-142. DOI PMID
  96. Hu HH, Börnert P, Hernando D, Kellman P, Ma J, Reeder S and Sirlin C. ISMRM workshop on fat-water separation: Insights, applications and progress in MRI. Magnetic Resonance in Medicine. 2012;68(2):378-388. DOI PMID
  97. Hines CDG, Agni R, Roen C, Rowland I, Hernando D, Bultman E, Horng D, Yu H, Shimakawa A, Brittain JH and Reeder SB. Validation of MRI biomarkers of hepatic steatosis in the presence of iron overload in the ob/ob mouse. Journal of Magnetic Resonance Imaging. 2012;35(4):844-851. DOI PMID
  98. Hernando D, Vigen KK, Shimakawa A and Reeder SB. R2* mapping in the presence of macroscopic B0 field variations. Magnetic Resonance in Medicine. 2012;68(3):830-840. DOI PMID
  99. Hernando D, Hines CDG, Yu H and Reeder SB. Addressing phase errors in fat-water imaging using a mixed magnitude/complex fitting method. Magnetic Resonance in Medicine. 2012;67(3):638-644. DOI PMID

    100. 2011

  100. Van AT, Hernando D and Sutton BP. Motion-induced phase error estimation and correction in 3D diffusion tensor imaging. IEEE Transactions on Medical Imaging. 2011;30(11):1933-1940. DOI PMID
  101. Hernando D, Karampinos DC, King KF, Haldar JP, Majumdar S, Georgiadis JG and Liang Z-P. Removal of olefinic fat chemical shift artifact in diffusion MRI. Magnetic Resonance in Medicine. 2011;65(3):692-701. DOI PMID
  102. Haldar JP, Hernando D and Liang Z-P. Compressed-sensing MRI with random encoding. IEEE Transactions on Medical Imaging. 2011;30(4):893-903. DOI PMID

    103. 2010

  103. Peng X, Nguyen H, Haldar J, Hernando D, Wang X-P and Liang Z-P. Correction of field inhomogeneity effects on limited k-space MRSI data using anatomical constraints. 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC’10. 2010:883-886. DOI PMID
  104. Kellman P, Hernando D and Arai AE. Myocardial Fat Imaging. Current Cardiovascular Imaging Reports. 2010;3(2):83-91. DOI
  105. Hernando D, Liang Z-P and Kellman P. Chemical shift-based water/fat separation: A comparison of signal models. Magnetic Resonance in Medicine. 2010;64(3):811-822. DOI PMID
  106. Hernando D, Kellman P, Haldar JP and Liang Z-P. Robust water/fat separation in the presence of large field inhomogeneities using a graph cut algorithm. Magnetic Resonance in Medicine. 2010;63(1):79-90. DOI PMID

    107. 2009

  107. Keilman P, Hernando D, Shah S, Zuehlsdorff S, Jerecic R, Mancini C, Liang Z-P and Arai AE. Multiecho dixon fat and water separation method for detecting fibrofatty infiltration in the myocardium. Magnetic Resonance in Medicine. 2009;61(1):215-221. DOI PMID
  108. Haldar JP, Hernando D and Liang Z-P. Super-Resolution reconstruction of mr image sequences with contrast modeling. Proceedings – 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009. 2009:266-269. DOI
  109. Haldar JP and Hernando D. Rank-constrained solutions to linear matrix equations using powerfactorization. IEEE Signal Processing Letters. 2009;16(7):584-587. DOI

    110. 2008

  110. Hernando D, Kellman P, Haldar JP and Liang Z-P. A network flow method for improved MR field map estimation in the presence of water and fat. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS’08 – “Personalized Healthcare through Technology”. 2008:82-85. PMID
  111. Hernando D, Haldar JP, Sutton BP, Ma J, Kellman P and Liang Z-P. Joint estimation of water/fat images and field inhomogeneity map. Magnetic Resonance in Medicine. 2008;59(3):571-580. DOI PMID
  112. Haldar JP, Hernando D, Song S-K and Liang Z-P. Anatomically constrained reconstruction from noisy data. Magnetic Resonance in Medicine. 2008;59(4):810-818. DOI PMID

    113. 2007

  113. Hernando D, Haldar J, Sutton B and Liang Z-P. Removal of lipid signal in mrsi using spatial-spectral constraints. 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro – Proceedings. 2007:1360-1363. DOI
  114. Haldar JP, Hernando D and Liang Z-P. Shaping spatial response functions for optimal estimation of compartmental signals from limited fourier data. 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro – Proceedings. 2007:1364-1367. DOI
  115. Haldar JP, Hernando D, Budde MD, Wang Q, Song S-K and Liang Z-P. High-resolution MR metabolic imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology – Proceedings. 2007:4324-4326. DOI PMID

    116. 2006

  116. Hernando D, Haldar J and Liang Z-P. Reduced-encoding MRI using higher-order generalized series. 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro – Proceedings. 2006;2006:29-32.
  117. Haldar JP, Jacob M, Ebel A, Zhu X, Schuff N, Hernando D, Sutton BP and Liang Z-P. Regularized inversion of noisy, incomplete MR spectroscopic imaging data with anatomical prior. 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro – Proceedings. 2006;2006:718-721.

    118. 2005

  118. Hernando D, Crespi V and Cybenko G. Efficient computation of the Hidden Markov model entropy for a given observation sequence. IEEE Transactions on Information Theory. 2005;51(7):2681-2685. DOI

    119. 2004

  119. Hernando D and Crespi V. Sampling theory for process detection with applications to surveillance and tracking. Proceedings of SPIE – The International Society for Optical Engineering. 2004;5403(PART 1):143-152. DOI